Investigative Studies

Investigative studies are key to improving our understanding of the nature of mental health disorders and often require healthy controls in addition to patient populations as volunteers.  

To read about our current investigative studies and to find out how to get involved, please see below. You can also view our Treatment Studies.

1. Non-Invasive Brain Stimulation: the Influence of Gender and Menstrual Phase

Aim: to assess the impact of gender, and within female gender stages of the menstrual cycle associated with high and low endogenous estrogen, on the effect of tDCS and rTMS. 

Participants: Healthy right-handed controls (18-40 years)

Project Status: Recruitment underway

Contact details

Cassandra Thomson

Email: cassandra.thomson@monash.edu

2. Optimising the use of Theta Burst TMS in Modifying Brain Activity

Aim: To better understand the optimal conditions for changing prefrontal cortical activity with Theta Burst Stimulation (TBS). Specifically, we will explore whether effects on cortical excitability are related to the intensity of stimulation, the frequency at which stimulation pluses are applied, the location of stimulation within the prefrontal cortex and repeated applications of stimulation.

Participants: Healthy controls.

Project status: Recruitment underway.

Contact details

Sung Wook Chung

Email: sung.chung@monash.edu

3. Optimizing TBS protocols for major depressive disorder:  A focus on affective processing bias 

Aim: To optimise non-invasive brain stimulation protocols (theta burst stimulation,TBS) for major depressive disorder with  a focus on affective processing bias.

Participants: Healthy controls and individuals with depression.

Project status: Recruitment underway.

Contact details

Ting Ting Cao

Email: tingting.cao@monash.edu

4. Enhancing cognitive processing in depression: An investigation of non-invasive electrical brain stimulation methods

Aim: To investigate the capacity of two different methods of non-invasive transcranial electrical stimulation to enhance cognitive processing, in both healthy individuals and those with major depression.

Participants: Healthy controls and individuals with major depression.

Project status: Recruitment underway

Contact details 

Oscar Murphy

Email: oscar.murphy@monash.edu

5. Inside the mind of an 'ultra'

Aim: To investigate the psychological, cognitive and psychophysiological attributes of ultra-runners.  Click here for more details

Participants: Healthy controls.

Project status: Actively recruiting participants  

Contact details

Greg Roebuck

Email: gregory.scott.roebuck@monash.edu

Cognitive Therapeutics Group Projects

1. Investigating the neurobiological and neurocognitive effects of multiple sessions of transcranscranial Direct Current Stimulation for working memory enhancement in people with schizophrenia

Participants: People with schizophrenia

Project status: Recruitment underway

Contact details 

Ms Hannah Coyle

Email: Hannah.Coyle@monash.edu

2. Using neuroscience to improve learning: Investigating the use of an optimised form of Transcranial Magnetic Stimulation

Participants: Healthy controls.

Project status: Recruitment on hold.

Contact details 

Dr Kate Hoy

Email: Kate.Hoy@monash.edu

3. Investigating the neurobiological and neurocognitve effects of transcranial direct current stimulation (tDCS)

Aim: To improve the ability of tDCS to modulate neuroplasticity and enhance cognition. Specifically, the project will explore the effect that factors such as electrode size, electrode montage, current strength and single versus repeated stimulation sessions have on cognitive function and underlying neurobiological processes through the use of TMS-EEG, MRI and neuropsychological assessments.  

Participants: Healthy controls.

Project status: Recruitment to begin shortly.  

Contact details

Aron Hill

Email: aron.hill@monash.edu

4. Brain stimulation, aging and cognition 

Aim: To investigate whether neural plasticity can be induced through brain stimulation in amnestic mild cognitive impairment (a-MCI), and whether there are differences in plasticity in the a-MCI group compared to younger and older healthy adults. Furthermore, the impact of repeated brain stimulation sessions on the cognitive performance and neural plasticity in participants with a-MCI will be also be addressed.

Participants: Healthy controls (18-35 or 56-75 years old); Participants with a-MCI (56-75 years old)

Project status: Actively recruiting participants.

Contact details

Melanie Emonson

Email: melanie.emonson@monash.edu

 

 

 

 

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