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Double-Blind randomised investigation of Tibolone as an adjunct to standard antidepressant treatment for relapsed and persistent depression in peri- and post-menopausal women
Aim: To examine the efficacy of a tissue-selective hormone treatment for menopausal depression.
Participants: Women between the ages of 45 and 65 years of age who have been diagnosed with Major Depressive Disorder (Major Depression) or are currently experiencing depressive symptoms that have relapsed during peri or post menopause.
Method: This is 12 week randomised controlled trial where participants will be randomly allocated to one of two study groups where they will receive either; 1) tibolone or 2) placebo daily. Researchers from the Women's Mental Health team will speak with participants fortnightly (over the phone) then monthly throughout the treatment trial to monitor how they are progressing.
Project status: Currently recruiting
Researchers: Professor Jayashri Kulkarni, Ms Emmy Gavrilidis, Dr Natalie Thomas, Dr Caroline Gurvich, Dr Rosie Worsley
Study Coordinator: Dr Natalie Thomas
Contact information: For more information, please contact Natalie Thomas on firstname.lastname@example.org or 9076 5033