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Clinical Trials in

Menstrual Related Disorder

Full Title

A randomised double-blinded interventional pilot of Zoely and Zoloft to treat Premenstrual Dysphoric Disorder

About the Trial

PMDD is a depressive disorder that occurs in cycles due to hormonal changes in the menstrual cycle. The most common pharmacological management options for PMDD are antidepressants and the combined oral contraceptive pill (COCP). This 21-week clinical trial will compare Zoely (COCP) and Zoloft (antidepressant) to examine which is more effective in reducing the symptoms of PMDD. The includes 2 months of pretreatment, 3 months of treatment, and 1 follow-up.

Zoely vs
Zoloft 

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Full Title

Theta Burst Transcranial Magnetic Stimulation to Treat Premenstrual Dysphoric Disorder

About the Trial

The overall objective of this pilot study is to evaluate whether Transcranial Magnetic Stimulation (TMS), a non-invasive form of brain stimulation, is effective in the treatment of PMDD symptoms in women. PMDD is a depressive disorder that occurs in cycles due to hormonal changes in the menstrual cycle. As TMS has proven to be helpful for some people who experience depression, it may be effective in improving mood and other psychological symptoms in PMDD.

TMS to
treat PMDD

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